COX2 inhibitory activity of abutilon indicum –An invitro study

C. Cinthura; Lakshmi Thangavelu; S. Rajeshkumar; Deepa Gurunadhan; R. Pradeep Kumar; Anitha Roy

doi:10.5958/0976-5506.2019.04131.7

COX2 inhibitory activity of abutilon indicum –An invitro study

C. Cinthura
, Lakshmi Thangavelu
, S. Rajeshkumar
, Deepa Gurunadhan
, R. Pradeep Kumar
, Anitha Roy

Saveetha Institute of Medical and Technical Sciences (Deemed to be University)

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

Aim: To analyse the COX2 inhibitory activity of Abutilon indicum. Objective: The main objective of this study is to analyse the COX2 inhibitory activity of Abutilon indicum Background: Prostaglandins are important mediators of the body’s response to pain and inflammation, and are formed from essential fatty acids found in cell membranes. This reaction is catalysed by cyclooxygenase, a membrane associated enzyme in two isoforms-COX-1 and COX-2. Abutilon indicum,commonly known as the Indian mallow is well known for its therapeutic values and further study of its COX-2 inhibitory activity is beneficial. Conclusion: Medicinal plants and shrubs which have little or no side effects have to be further investigated. Further study on its COX-2 inhibition will increase its therapeutic value also as an anti-inflammatory with added benefits.

Original language	English
Pages (from-to)	3524-3526
Number of pages	3
Journal	Indian Journal of Public Health Research and Development
Volume	10
Issue number	11
DOIs	https://doi.org/10.5958/0976-5506.2019.04131.7
State	Published - Nov 2019
Externally published	Yes

Keywords

Anti-arthritic
COX2 Inhibition
Ethnomedicinal
Medicinal uses
Prostaglandin

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10.5958/0976-5506.2019.04131.7

Cite this

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title = "COX2 inhibitory activity of abutilon indicum –An invitro study",

abstract = "Aim: To analyse the COX2 inhibitory activity of Abutilon indicum. Objective: The main objective of this study is to analyse the COX2 inhibitory activity of Abutilon indicum Background: Prostaglandins are important mediators of the body{\textquoteright}s response to pain and inflammation, and are formed from essential fatty acids found in cell membranes. This reaction is catalysed by cyclooxygenase, a membrane associated enzyme in two isoforms-COX-1 and COX-2. Abutilon indicum,commonly known as the Indian mallow is well known for its therapeutic values and further study of its COX-2 inhibitory activity is beneficial. Conclusion: Medicinal plants and shrubs which have little or no side effects have to be further investigated. Further study on its COX-2 inhibition will increase its therapeutic value also as an anti-inflammatory with added benefits.",

keywords = "Anti-arthritic, COX2 Inhibition, Ethnomedicinal, Medicinal uses, Prostaglandin",

author = "C. Cinthura and Lakshmi Thangavelu and S. Rajeshkumar and Deepa Gurunadhan and \{Pradeep Kumar\}, R. and Anitha Roy",

year = "2019",

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language = "English",

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journal = "Indian Journal of Public Health Research and Development",

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T1 - COX2 inhibitory activity of abutilon indicum –An invitro study

AU - Cinthura, C.

AU - Thangavelu, Lakshmi

AU - Rajeshkumar, S.

AU - Gurunadhan, Deepa

AU - Pradeep Kumar, R.

AU - Roy, Anitha

PY - 2019/11

Y1 - 2019/11

N2 - Aim: To analyse the COX2 inhibitory activity of Abutilon indicum. Objective: The main objective of this study is to analyse the COX2 inhibitory activity of Abutilon indicum Background: Prostaglandins are important mediators of the body’s response to pain and inflammation, and are formed from essential fatty acids found in cell membranes. This reaction is catalysed by cyclooxygenase, a membrane associated enzyme in two isoforms-COX-1 and COX-2. Abutilon indicum,commonly known as the Indian mallow is well known for its therapeutic values and further study of its COX-2 inhibitory activity is beneficial. Conclusion: Medicinal plants and shrubs which have little or no side effects have to be further investigated. Further study on its COX-2 inhibition will increase its therapeutic value also as an anti-inflammatory with added benefits.

AB - Aim: To analyse the COX2 inhibitory activity of Abutilon indicum. Objective: The main objective of this study is to analyse the COX2 inhibitory activity of Abutilon indicum Background: Prostaglandins are important mediators of the body’s response to pain and inflammation, and are formed from essential fatty acids found in cell membranes. This reaction is catalysed by cyclooxygenase, a membrane associated enzyme in two isoforms-COX-1 and COX-2. Abutilon indicum,commonly known as the Indian mallow is well known for its therapeutic values and further study of its COX-2 inhibitory activity is beneficial. Conclusion: Medicinal plants and shrubs which have little or no side effects have to be further investigated. Further study on its COX-2 inhibition will increase its therapeutic value also as an anti-inflammatory with added benefits.

KW - Anti-arthritic

KW - COX2 Inhibition

KW - Ethnomedicinal

KW - Medicinal uses

KW - Prostaglandin

UR - https://www.scopus.com/pages/publications/85089764549

U2 - 10.5958/0976-5506.2019.04131.7

DO - 10.5958/0976-5506.2019.04131.7

M3 - Article

AN - SCOPUS:85089764549

SN - 0976-0245

VL - 10

SP - 3524

EP - 3526

JO - Indian Journal of Public Health Research and Development

JF - Indian Journal of Public Health Research and Development

IS - 11

ER -

COX2 inhibitory activity of abutilon indicum –An invitro study

Abstract

Keywords

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