Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases

Md Khabeer Azhar; Saleha Anwar; Gulam Mustafa Hasan; Anas Shamsi; Asimul Islam; Suhel Parvez; Md Imtaiyaz Hassan

doi:10.3390/nu15194297

Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases

Md Khabeer Azhar
, Saleha Anwar
, Gulam Mustafa Hasan
, Anas Shamsi
, Asimul Islam
, Suhel Parvez
, Md Imtaiyaz Hassan

Deanship of Research and Graduate Studies

Jamia Millia Islamia
Jamia Hamdard University
Prince Sattam Bin Abdulaziz University

Research output: Contribution to journal › Review article › peer-review

56 Scopus citations

Abstract

Phytochemicals are abundantly occurring natural compounds extracted from plant sources. Rosmarinic acid (RA) is an abundant phytochemical of Lamiaceae species with various therapeutic implications for human health. In recent years, natural compounds have gained significant attention as adjuvant and complementary therapies to existing medications for various diseases. RA has gained popularity due to its anti-inflammatory and antioxidant properties and its roles in various life-threatening conditions, such as cancer, neurodegeneration, diabetes, etc. The present review aims to offer a comprehensive insight into the multifaceted therapeutic properties of RA, including its potential as an anticancer agent, neuroprotective effects, and antidiabetic potential. Based on the available evidences, RA could be considered a potential dietary component for treating various diseases, including cancer, diabetes and neurodegenerative disorders.

Original language	English
Article number	4297
Journal	Nutrients
Volume	15
Issue number	19
DOIs	https://doi.org/10.3390/nu15194297
State	Published - Oct 2023

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

anti-inflammatory
anticancer therapeutics
antioxidant
drug discovery
neurodegenerative diseases
phytochemicals
rosmarinic acid

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10.3390/nu15194297

Cite this

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title = "Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases",

abstract = "Phytochemicals are abundantly occurring natural compounds extracted from plant sources. Rosmarinic acid (RA) is an abundant phytochemical of Lamiaceae species with various therapeutic implications for human health. In recent years, natural compounds have gained significant attention as adjuvant and complementary therapies to existing medications for various diseases. RA has gained popularity due to its anti-inflammatory and antioxidant properties and its roles in various life-threatening conditions, such as cancer, neurodegeneration, diabetes, etc. The present review aims to offer a comprehensive insight into the multifaceted therapeutic properties of RA, including its potential as an anticancer agent, neuroprotective effects, and antidiabetic potential. Based on the available evidences, RA could be considered a potential dietary component for treating various diseases, including cancer, diabetes and neurodegenerative disorders.",

keywords = "anti-inflammatory, anticancer therapeutics, antioxidant, drug discovery, neurodegenerative diseases, phytochemicals, rosmarinic acid",

author = "Azhar, \{Md Khabeer\} and Saleha Anwar and Hasan, \{Gulam Mustafa\} and Anas Shamsi and Asimul Islam and Suhel Parvez and Hassan, \{Md Imtaiyaz\}",

note = "Publisher Copyright: {\textcopyright} 2023 by the authors.",

year = "2023",

month = oct,

doi = "10.3390/nu15194297",

language = "English",

volume = "15",

journal = "Nutrients",

issn = "2072-6643",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

number = "19",

}

TY - JOUR

T1 - Comprehensive Insights into Biological Roles of Rosmarinic Acid

T2 - Implications in Diabetes, Cancer and Neurodegenerative Diseases

AU - Azhar, Md Khabeer

AU - Anwar, Saleha

AU - Hasan, Gulam Mustafa

AU - Shamsi, Anas

AU - Islam, Asimul

AU - Parvez, Suhel

AU - Hassan, Md Imtaiyaz

PY - 2023/10

Y1 - 2023/10

N2 - Phytochemicals are abundantly occurring natural compounds extracted from plant sources. Rosmarinic acid (RA) is an abundant phytochemical of Lamiaceae species with various therapeutic implications for human health. In recent years, natural compounds have gained significant attention as adjuvant and complementary therapies to existing medications for various diseases. RA has gained popularity due to its anti-inflammatory and antioxidant properties and its roles in various life-threatening conditions, such as cancer, neurodegeneration, diabetes, etc. The present review aims to offer a comprehensive insight into the multifaceted therapeutic properties of RA, including its potential as an anticancer agent, neuroprotective effects, and antidiabetic potential. Based on the available evidences, RA could be considered a potential dietary component for treating various diseases, including cancer, diabetes and neurodegenerative disorders.

AB - Phytochemicals are abundantly occurring natural compounds extracted from plant sources. Rosmarinic acid (RA) is an abundant phytochemical of Lamiaceae species with various therapeutic implications for human health. In recent years, natural compounds have gained significant attention as adjuvant and complementary therapies to existing medications for various diseases. RA has gained popularity due to its anti-inflammatory and antioxidant properties and its roles in various life-threatening conditions, such as cancer, neurodegeneration, diabetes, etc. The present review aims to offer a comprehensive insight into the multifaceted therapeutic properties of RA, including its potential as an anticancer agent, neuroprotective effects, and antidiabetic potential. Based on the available evidences, RA could be considered a potential dietary component for treating various diseases, including cancer, diabetes and neurodegenerative disorders.

KW - anti-inflammatory

KW - anticancer therapeutics

KW - antioxidant

KW - drug discovery

KW - neurodegenerative diseases

KW - phytochemicals

KW - rosmarinic acid

UR - https://www.scopus.com/pages/publications/85173798062

U2 - 10.3390/nu15194297

DO - 10.3390/nu15194297

M3 - Review article

C2 - 37836581

AN - SCOPUS:85173798062

SN - 2072-6643

VL - 15

JO - Nutrients

JF - Nutrients

IS - 19

M1 - 4297

ER -

Comprehensive Insights into Biological Roles of Rosmarinic Acid: Implications in Diabetes, Cancer and Neurodegenerative Diseases

Abstract

UN SDGs

Keywords

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