Biofilms and the plasmid maintenance question

Mudassar Imran; Don Jones; Hal Smith

doi:10.1016/j.mbs.2004.10.008

Biofilms and the plasmid maintenance question

Mudassar Imran
, Don Jones
, Hal Smith

Arizona State University

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

Can a conjugative plasmid encoding enhanced biofilm forming abilities for its bacterial host facilitate the persistence of the plasmid in a bacterial population despite conferring diminished growth rate and segregative plasmid loss on its bearers? We construct a mathematical model in a chemostat and in a plug flow environment to answer this question. Explicit conditions for an affirmative answer are derived. Numerical simulations support the conclusion.

Original language	English
Pages (from-to)	183-204
Number of pages	22
Journal	Mathematical Biosciences
Volume	193
Issue number	2
DOIs	https://doi.org/10.1016/j.mbs.2004.10.008
State	Published - Feb 2005
Externally published	Yes

Keywords

Bacterial wall growth
Biofilm
Chemostat
Conjugation
Model
Plasmid
Plug flow
Segregation

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10.1016/j.mbs.2004.10.008

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abstract = "Can a conjugative plasmid encoding enhanced biofilm forming abilities for its bacterial host facilitate the persistence of the plasmid in a bacterial population despite conferring diminished growth rate and segregative plasmid loss on its bearers? We construct a mathematical model in a chemostat and in a plug flow environment to answer this question. Explicit conditions for an affirmative answer are derived. Numerical simulations support the conclusion.",

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AU - Jones, Don

AU - Smith, Hal

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AB - Can a conjugative plasmid encoding enhanced biofilm forming abilities for its bacterial host facilitate the persistence of the plasmid in a bacterial population despite conferring diminished growth rate and segregative plasmid loss on its bearers? We construct a mathematical model in a chemostat and in a plug flow environment to answer this question. Explicit conditions for an affirmative answer are derived. Numerical simulations support the conclusion.

KW - Bacterial wall growth

KW - Biofilm

KW - Chemostat

KW - Conjugation

KW - Model

KW - Plasmid

KW - Plug flow

KW - Segregation

UR - https://www.scopus.com/pages/publications/14644403102

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EP - 204

JO - Mathematical Biosciences

JF - Mathematical Biosciences

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ER -

Biofilms and the plasmid maintenance question

Abstract

Keywords

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