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Antimicrobial Activity of Hydrocotyle umbellata L. Assisted Iron Oxide Nanoparticles against Urinary Tract Infection Pathogens

  • Sulochana Govindharaj
  • , A. T. Mithun Athiraj
  • , Jyotsna Saradha Prabhu
  • , Lakshmi Thangavelu
  • , Rajeshkumar Shanmugam
  • Saveetha Institute of Medical and Technical Sciences (Deemed to be University)

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Iron Oxide Nanoparticles have shown and proven promising effects in the field of biomedicals because of their special physico-chemical features. Hydrocotyle umbellata L, has the ability to metabolise both organic and inorganic substances proving to be beneficial. The main purpose of green chemistry is to develop products in a way that prevents the environment from getting polluted and to reduce the amount of waste products. The purpose of this study is to analyze the antimicrobial activity of Hydrocotyle umbellata mediated iron oxide nanoparticles. The time kill curve analysis was done to check the bactericidal properties of the nanoparticle against Escherichia coli, Enterococcus faecalis, Staphylococcus aureus and Streptococcus mutans. The plant solution was first prepared using the plant extract. Followed by the preparation of the nanoparticle solution. Antimicrobial activity and Time kill curve analysis was done to check the properties of the iron oxide nanoparticle which was synthesized by the plant Hydrocotyle umbellata against UTI pathogens. The results have been graphically represented and it proves that the iron oxide nanoparticles are bactericidal, not only preventing the further growth of bacterias but also killing the remnants of the bacterias. This study concludes that iron oxide nanoparticles that were synthesized using the plant Hydrocotyle umbellata have an amazing antimicrobial property against UTI pathogens proving to be of various advantages.

Original languageEnglish
Pages (from-to)385-394
Number of pages10
JournalNanotechnology Perceptions
Volume20
Issue numberS7
DOIs
StatePublished - 2024
Externally publishedYes

Keywords

  • Antimicrobial property
  • Green synthesized
  • UTI pathogens
  • iron oxide nanoparticles

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