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Anti-Inflammatory and Anti-Oxidant Activity of L. Angustifolia Mediated Carbon Nanoparticles Synthesized Using Microwave Heat Method

  • Pradeep Manigandan
  • , D. Raja Sujith Kumar
  • , Jayaashree Parameswaran
  • , Rajeshkumar Shanmugam
  • , Lakshmi Thangavelu
  • Saveetha Institute of Medical and Technical Sciences (Deemed to be University)

Research output: Contribution to journalArticlepeer-review

Abstract

This research aims to study the antioxidant, anti-inflammatory, antimicrobial, and cytotoxic activity of carbon nanoparticles biosynthesized using lavender extract. Green synthesis of CNPs using Lavandula angustifolia flower extract and is evaluated for antioxidant activity-DPPH, H₂O₂, FRAP, ABTS assay, anti-inflammatory activity-bovine serum albumin, egg albumin denaturation, human RBC membrane stabilization assay, antimicrobial activity-agar well diffusion method and cytotoxic activity using brine shrimp lethality assay. Biosynthesized CNPs showed a maximum zone of inhibition of in the highest tested concentration of 100µg/ml. The results show that L. angustifolia-mediated CNPs are less cytotoxic and show excellent antioxidant, anti-inflammatory, and antimicrobial activity. Further research is needed on carbon nanoparticles to assess their biomedical activities to be used in future therapeutics.

Original languageEnglish
Pages (from-to)290-303
Number of pages14
JournalNanotechnology Perceptions
Volume20
Issue numberS7
DOIs
StatePublished - 2024
Externally publishedYes

Keywords

  • Anti-inflammatory
  • antioxidant
  • biomedical applications
  • carbon nanoparticles
  • egg albumin

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