An overview of recent advances in insulin delivery and wearable technology for effective management of diabetes

Sujeet Kumar Raj; M. Ravindra Babu; Sukriti Vishwas; M. V.N.L. Chaitanya; Vancha Harish; Gaurav Gupta; Dinesh Kumar Chellappan; Kamal Dua; Sachin Kumar Singh

doi:10.1016/j.jddst.2022.103728

An overview of recent advances in insulin delivery and wearable technology for effective management of diabetes

Sujeet Kumar Raj
, M. Ravindra Babu
, Sukriti Vishwas
, M. V.N.L. Chaitanya
, Vancha Harish
, Gaurav Gupta
, Dinesh Kumar Chellappan
, Kamal Dua
, Sachin Kumar Singh

Lovely Professional University
Suresh Gyan Vihar University
Saveetha Institute of Medical and Technical Sciences (Deemed to be University)
Uttaranchal University
International Medical University
University of Technology Sydney

Research output: Contribution to journal › Review article › peer-review

7 Scopus citations

Abstract

Diabetes mellitus (DM) continues to impact a considerable section of the population. Insulin (IN) is required on a daily basis by the majority of people infected. Diabetes had a huge impact on patients' life prior to the introduction of the first produced IN in 1978. Significant progress has been made in the management of DM as technology and human inventiveness have prevailed. Now, patients have the choice of choosing their INdelivery mode, and they are easier to administer. The current review focuses on the traditional IN therapy and evolution of IN analogues (IN like substances). Various routes of administrations of IN such as oral, transdermal, intranasalare also discussed. The recent novel drug delivery systems explored for the delivery of IN along with the continuous glucose monitoring systems (CGM) for DM management are also highlighted.

Original language	English
Article number	103728
Journal	Journal of Drug Delivery Science and Technology
Volume	75
DOIs	https://doi.org/10.1016/j.jddst.2022.103728
State	Published - Sep 2022
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Diabetes mellitus
Electroporation
Insulin
Insulin analogues
Intranasal delivery
Iontophoresis
NDDS
Transdermal delivery
Wearable technology

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10.1016/j.jddst.2022.103728

Cite this

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title = "An overview of recent advances in insulin delivery and wearable technology for effective management of diabetes",

abstract = "Diabetes mellitus (DM) continues to impact a considerable section of the population. Insulin (IN) is required on a daily basis by the majority of people infected. Diabetes had a huge impact on patients' life prior to the introduction of the first produced IN in 1978. Significant progress has been made in the management of DM as technology and human inventiveness have prevailed. Now, patients have the choice of choosing their INdelivery mode, and they are easier to administer. The current review focuses on the traditional IN therapy and evolution of IN analogues (IN like substances). Various routes of administrations of IN such as oral, transdermal, intranasalare also discussed. The recent novel drug delivery systems explored for the delivery of IN along with the continuous glucose monitoring systems (CGM) for DM management are also highlighted.",

keywords = "Diabetes mellitus, Electroporation, Insulin, Insulin analogues, Intranasal delivery, Iontophoresis, NDDS, Transdermal delivery, Wearable technology",

author = "Raj, \{Sujeet Kumar\} and Babu, \{M. Ravindra\} and Sukriti Vishwas and Chaitanya, \{M. V.N.L.\} and Vancha Harish and Gaurav Gupta and Chellappan, \{Dinesh Kumar\} and Kamal Dua and Singh, \{Sachin Kumar\}",

note = "Publisher Copyright: {\textcopyright} 2022 Elsevier B.V.",

year = "2022",

month = sep,

doi = "10.1016/j.jddst.2022.103728",

language = "English",

volume = "75",

journal = "Journal of Drug Delivery Science and Technology",

issn = "1773-2247",

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T1 - An overview of recent advances in insulin delivery and wearable technology for effective management of diabetes

AU - Raj, Sujeet Kumar

AU - Babu, M. Ravindra

AU - Vishwas, Sukriti

AU - Chaitanya, M. V.N.L.

AU - Harish, Vancha

AU - Gupta, Gaurav

AU - Chellappan, Dinesh Kumar

AU - Dua, Kamal

AU - Singh, Sachin Kumar

PY - 2022/9

Y1 - 2022/9

N2 - Diabetes mellitus (DM) continues to impact a considerable section of the population. Insulin (IN) is required on a daily basis by the majority of people infected. Diabetes had a huge impact on patients' life prior to the introduction of the first produced IN in 1978. Significant progress has been made in the management of DM as technology and human inventiveness have prevailed. Now, patients have the choice of choosing their INdelivery mode, and they are easier to administer. The current review focuses on the traditional IN therapy and evolution of IN analogues (IN like substances). Various routes of administrations of IN such as oral, transdermal, intranasalare also discussed. The recent novel drug delivery systems explored for the delivery of IN along with the continuous glucose monitoring systems (CGM) for DM management are also highlighted.

AB - Diabetes mellitus (DM) continues to impact a considerable section of the population. Insulin (IN) is required on a daily basis by the majority of people infected. Diabetes had a huge impact on patients' life prior to the introduction of the first produced IN in 1978. Significant progress has been made in the management of DM as technology and human inventiveness have prevailed. Now, patients have the choice of choosing their INdelivery mode, and they are easier to administer. The current review focuses on the traditional IN therapy and evolution of IN analogues (IN like substances). Various routes of administrations of IN such as oral, transdermal, intranasalare also discussed. The recent novel drug delivery systems explored for the delivery of IN along with the continuous glucose monitoring systems (CGM) for DM management are also highlighted.

KW - Diabetes mellitus

KW - Electroporation

KW - Insulin

KW - Insulin analogues

KW - Intranasal delivery

KW - Iontophoresis

KW - NDDS

KW - Transdermal delivery

KW - Wearable technology

UR - https://www.scopus.com/pages/publications/85136574630

U2 - 10.1016/j.jddst.2022.103728

DO - 10.1016/j.jddst.2022.103728

M3 - Review article

AN - SCOPUS:85136574630

SN - 1773-2247

VL - 75

JO - Journal of Drug Delivery Science and Technology

JF - Journal of Drug Delivery Science and Technology

M1 - 103728

ER -

An overview of recent advances in insulin delivery and wearable technology for effective management of diabetes

Abstract

UN SDGs

Keywords

Access to Document

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Cite this