An appraisal of the current scenario in vaccine research for COVID-19

Wai Chin Chong; Dinesh K. Chellappan; Shakti D. Shukla; Gregory M. Peterson; Rahul P. Patel; Niraj Kumar Jha; Rajaraman D. Eri; Kamal Dua; Murtaza M. Tambuwala; Madhur D. Shastri

doi:10.3390/v13071397

An appraisal of the current scenario in vaccine research for COVID-19

Wai Chin Chong
, Dinesh K. Chellappan
, Shakti D. Shukla
, Gregory M. Peterson
, Rahul P. Patel
, Niraj Kumar Jha
, Rajaraman D. Eri
, Kamal Dua
, Murtaza M. Tambuwala
, Madhur D. Shastri

Monash University
International Medical University
University of Technology Sydney
University of Tasmania
Sharda University
Ulster University

Research output: Contribution to journal › Review article › peer-review

5 Scopus citations

Abstract

The recent coronavirus disease 2019 (COVID-19) outbreak has drawn global attention, affecting millions, disrupting economies and healthcare modalities. With its high infection rate, COVID-19 has caused a colossal health crisis worldwide. While information on the comprehensive nature of this infectious agent, SARS-CoV-2, still remains obscure, ongoing genomic studies have been successful in identifying its genomic sequence and the presenting antigen. These may serve as promising, potential therapeutic targets in the effective management of COVID-19. In an attempt to establish herd immunity, massive efforts have been directed and driven toward developing vaccines against the SARS-CoV-2 pathogen. This review, in this direction, is aimed at providing the current scenario and future perspectives in the development of vaccines against SARS-CoV-2.

Original language	English
Article number	1397
Journal	Viruses
Volume	13
Issue number	7
DOIs	https://doi.org/10.3390/v13071397
State	Published - Jul 2021
Externally published	Yes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

COVID-19
Immunity
SARS-CoV-2
Therapeutic targets
Vaccines

Access to Document

10.3390/v13071397

Cite this

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title = "An appraisal of the current scenario in vaccine research for COVID-19",

abstract = "The recent coronavirus disease 2019 (COVID-19) outbreak has drawn global attention, affecting millions, disrupting economies and healthcare modalities. With its high infection rate, COVID-19 has caused a colossal health crisis worldwide. While information on the comprehensive nature of this infectious agent, SARS-CoV-2, still remains obscure, ongoing genomic studies have been successful in identifying its genomic sequence and the presenting antigen. These may serve as promising, potential therapeutic targets in the effective management of COVID-19. In an attempt to establish herd immunity, massive efforts have been directed and driven toward developing vaccines against the SARS-CoV-2 pathogen. This review, in this direction, is aimed at providing the current scenario and future perspectives in the development of vaccines against SARS-CoV-2.",

keywords = "COVID-19, Immunity, SARS-CoV-2, Therapeutic targets, Vaccines",

author = "Chong, \{Wai Chin\} and Chellappan, \{Dinesh K.\} and Shukla, \{Shakti D.\} and Peterson, \{Gregory M.\} and Patel, \{Rahul P.\} and Jha, \{Niraj Kumar\} and Eri, \{Rajaraman D.\} and Kamal Dua and Tambuwala, \{Murtaza M.\} and Shastri, \{Madhur D.\}",

note = "Publisher Copyright: {\textcopyright} 2021 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2021",

month = jul,

doi = "10.3390/v13071397",

language = "English",

volume = "13",

journal = "Viruses",

issn = "1999-4915",

publisher = "Multidisciplinary Digital Publishing Institute (MDPI)",

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AU - Chong, Wai Chin

AU - Chellappan, Dinesh K.

AU - Shukla, Shakti D.

AU - Peterson, Gregory M.

AU - Patel, Rahul P.

AU - Jha, Niraj Kumar

AU - Eri, Rajaraman D.

AU - Dua, Kamal

AU - Tambuwala, Murtaza M.

AU - Shastri, Madhur D.

PY - 2021/7

Y1 - 2021/7

N2 - The recent coronavirus disease 2019 (COVID-19) outbreak has drawn global attention, affecting millions, disrupting economies and healthcare modalities. With its high infection rate, COVID-19 has caused a colossal health crisis worldwide. While information on the comprehensive nature of this infectious agent, SARS-CoV-2, still remains obscure, ongoing genomic studies have been successful in identifying its genomic sequence and the presenting antigen. These may serve as promising, potential therapeutic targets in the effective management of COVID-19. In an attempt to establish herd immunity, massive efforts have been directed and driven toward developing vaccines against the SARS-CoV-2 pathogen. This review, in this direction, is aimed at providing the current scenario and future perspectives in the development of vaccines against SARS-CoV-2.

AB - The recent coronavirus disease 2019 (COVID-19) outbreak has drawn global attention, affecting millions, disrupting economies and healthcare modalities. With its high infection rate, COVID-19 has caused a colossal health crisis worldwide. While information on the comprehensive nature of this infectious agent, SARS-CoV-2, still remains obscure, ongoing genomic studies have been successful in identifying its genomic sequence and the presenting antigen. These may serve as promising, potential therapeutic targets in the effective management of COVID-19. In an attempt to establish herd immunity, massive efforts have been directed and driven toward developing vaccines against the SARS-CoV-2 pathogen. This review, in this direction, is aimed at providing the current scenario and future perspectives in the development of vaccines against SARS-CoV-2.

KW - COVID-19

KW - Immunity

KW - SARS-CoV-2

KW - Therapeutic targets

KW - Vaccines

UR - https://www.scopus.com/pages/publications/85111381173

U2 - 10.3390/v13071397

DO - 10.3390/v13071397

M3 - Review article

C2 - 34372603

AN - SCOPUS:85111381173

SN - 1999-4915

VL - 13

JO - Viruses

JF - Viruses

IS - 7

M1 - 1397

ER -

An appraisal of the current scenario in vaccine research for COVID-19

Abstract

UN SDGs

Keywords

Access to Document

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