A Perspective Review on Animal Coronaviruses: From Infection Insights to Preventive Measures and Antiviral Advancements

Tanvi; Rajat Goyal; Rupesh K. Gautam; Kashish Wilson; Kajal Garg; Tanmay Sharma; Sumeet Gupta; Sachin Kumar Singh; Haider Ali; Gaurav Gupta; Md Sadique Hussain

doi:10.2174/0126667975359293250210050445

A Perspective Review on Animal Coronaviruses: From Infection Insights to Preventive Measures and Antiviral Advancements

Tanvi
, Rajat Goyal
, Rupesh K. Gautam
, Kashish Wilson
, Kajal Garg
, Tanmay Sharma
, Sumeet Gupta
, Sachin Kumar Singh
, Haider Ali
, Gaurav Gupta
, Md Sadique Hussain

Center of Medical and Bio-allied Health Sciences Research (CMBHSR)

M.M College of Pharmacy
Indore Institute of Pharmacy
Kurukshetra University
Lovely Professional University
Sunway University
University of Technology Sydney
Saveetha Institute of Medical and Technical Sciences (Deemed to be University)
Kyrgyz State Medical College
Chitkara University
Uttaranchal University

Research output: Contribution to journal › Review article › peer-review

Abstract

Animal coronaviruses (CoVs) have emerged as significant pathogens with considerable implications for both animal and human health. This review provides an in-depth analysis of the origins, transmission dynamics, and pathogenic mechanisms of animal CoVs. We examine the viral entry, replication processes, and immune evasion strategies that enable CoVs to infect a variety of host species. Additionally, the review highlights recent advancements in prevention and therapeutic strategies, including the development of species-specific vaccines, enhanced biosecurity measures, and surveillance systems aimed at controlling zoonotic spillover. Furthermore, we discuss the latest antiviral strategies, including repurposed drugs, targeted molecular therapies, and the development of novel antiviral agents. This review emphasizes the importance of interdisciplinary research in advancing our understanding of animal CoVs and in developing effective interventions to mitigate their impact on global health.

Original language	English
Journal	Coronaviruses
Volume	7
Issue number	3
DOIs	https://doi.org/10.2174/0126667975359293250210050445
State	Published - 2026

Keywords

Animal coronaviruses
RNA viruses
antiviral therapies
immune evasion strategies
zoonotic spillover
zoonotic transmission

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10.2174/0126667975359293250210050445

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@article{49eb4a61dcb64fd7b9d52322e8cca6e1,

title = "A Perspective Review on Animal Coronaviruses: From Infection Insights to Preventive Measures and Antiviral Advancements",

abstract = "Animal coronaviruses (CoVs) have emerged as significant pathogens with considerable implications for both animal and human health. This review provides an in-depth analysis of the origins, transmission dynamics, and pathogenic mechanisms of animal CoVs. We examine the viral entry, replication processes, and immune evasion strategies that enable CoVs to infect a variety of host species. Additionally, the review highlights recent advancements in prevention and therapeutic strategies, including the development of species-specific vaccines, enhanced biosecurity measures, and surveillance systems aimed at controlling zoonotic spillover. Furthermore, we discuss the latest antiviral strategies, including repurposed drugs, targeted molecular therapies, and the development of novel antiviral agents. This review emphasizes the importance of interdisciplinary research in advancing our understanding of animal CoVs and in developing effective interventions to mitigate their impact on global health.",

keywords = "Animal coronaviruses, RNA viruses, antiviral therapies, immune evasion strategies, zoonotic spillover, zoonotic transmission",

author = "Tanvi and Rajat Goyal and Gautam, \{Rupesh K.\} and Kashish Wilson and Kajal Garg and Tanmay Sharma and Sumeet Gupta and Singh, \{Sachin Kumar\} and Haider Ali and Gaurav Gupta and Hussain, \{Md Sadique\}",

note = "Publisher Copyright: 2026, Bentham Science Publishers",

year = "2026",

doi = "10.2174/0126667975359293250210050445",

language = "English",

volume = "7",

journal = "Coronaviruses",

issn = "2666-7967",

publisher = "Bentham Science Publishers",

number = "3",

}

TY - JOUR

T1 - A Perspective Review on Animal Coronaviruses

T2 - From Infection Insights to Preventive Measures and Antiviral Advancements

AU - Tanvi,

AU - Goyal, Rajat

AU - Gautam, Rupesh K.

AU - Wilson, Kashish

AU - Garg, Kajal

AU - Sharma, Tanmay

AU - Gupta, Sumeet

AU - Singh, Sachin Kumar

AU - Ali, Haider

AU - Gupta, Gaurav

AU - Hussain, Md Sadique

N1 - Publisher Copyright: 2026, Bentham Science Publishers

PY - 2026

Y1 - 2026

N2 - Animal coronaviruses (CoVs) have emerged as significant pathogens with considerable implications for both animal and human health. This review provides an in-depth analysis of the origins, transmission dynamics, and pathogenic mechanisms of animal CoVs. We examine the viral entry, replication processes, and immune evasion strategies that enable CoVs to infect a variety of host species. Additionally, the review highlights recent advancements in prevention and therapeutic strategies, including the development of species-specific vaccines, enhanced biosecurity measures, and surveillance systems aimed at controlling zoonotic spillover. Furthermore, we discuss the latest antiviral strategies, including repurposed drugs, targeted molecular therapies, and the development of novel antiviral agents. This review emphasizes the importance of interdisciplinary research in advancing our understanding of animal CoVs and in developing effective interventions to mitigate their impact on global health.

AB - Animal coronaviruses (CoVs) have emerged as significant pathogens with considerable implications for both animal and human health. This review provides an in-depth analysis of the origins, transmission dynamics, and pathogenic mechanisms of animal CoVs. We examine the viral entry, replication processes, and immune evasion strategies that enable CoVs to infect a variety of host species. Additionally, the review highlights recent advancements in prevention and therapeutic strategies, including the development of species-specific vaccines, enhanced biosecurity measures, and surveillance systems aimed at controlling zoonotic spillover. Furthermore, we discuss the latest antiviral strategies, including repurposed drugs, targeted molecular therapies, and the development of novel antiviral agents. This review emphasizes the importance of interdisciplinary research in advancing our understanding of animal CoVs and in developing effective interventions to mitigate their impact on global health.

KW - Animal coronaviruses

KW - RNA viruses

KW - antiviral therapies

KW - immune evasion strategies

KW - zoonotic spillover

KW - zoonotic transmission

UR - https://www.scopus.com/pages/publications/105039523243

U2 - 10.2174/0126667975359293250210050445

DO - 10.2174/0126667975359293250210050445

M3 - Review article

AN - SCOPUS:105039523243

SN - 2666-7967

VL - 7

JO - Coronaviruses

JF - Coronaviruses

IS - 3

ER -

A Perspective Review on Animal Coronaviruses: From Infection Insights to Preventive Measures and Antiviral Advancements

Abstract

Keywords

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