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A model of electrokinetic platform for separation of different sizes of biological particles

  • Helwan University
  • American University in Cairo

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

The dielectrophoresis (DEP) phenomena is a motion of uncharged polarizable particles in the direction of most field strength site within a non-uniform electric field. Unlike various techniques, the DEP is an effective technique for particles manipulation and separation of biological particles. The manipulation and separation of biological cells are necessary to various biomedical applications such as cell biology analysis, diagnostics, and therapeutics. The traveling-wave dielectrophoresis (twDEP) and levitation are major subcategories of electro-kinetic motions that are generated as a result of the interaction between a non-uniform electric field and polarizable particles. This article presents a model of an electrokinetic platform that has a working principle of dielectrophoresis phenomena and Printed Circuit Board (PCB) technology for separation of different sizes of biological particles such as microbeads (simulated biological cells) and the blood formed elements (platelets and red blood cells (RBCs)) using two configurations of microelectrodes (traveling and levitation).

Original languageEnglish
Title of host publicationProceedings of the International Conference on Advanced Intelligent Systems and Informatics 2017
EditorsMohamed F. Tolba, Tarek Gaber, Khaled Shaalan, Aboul Ella Hassanien
PublisherSpringer Verlag
Pages118-128
Number of pages11
ISBN (Print)9783319648606
DOIs
StatePublished - 2018
Externally publishedYes
Event3rd International Conference on Advanced Intelligent Systems and Informatics, AISI 2017 - Cairo, Egypt
Duration: 9 Sep 201711 Sep 2017

Publication series

NameAdvances in Intelligent Systems and Computing
Volume639
ISSN (Print)2194-5357

Conference

Conference3rd International Conference on Advanced Intelligent Systems and Informatics, AISI 2017
Country/TerritoryEgypt
CityCairo
Period9/09/1711/09/17

Keywords

  • COMSOL
  • Dielectrophoresis
  • Levitation
  • Microbeads
  • Platelets
  • Red blood cells
  • Separation
  • Traveling wave

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