A Convenient Synthetic Route of Diethyl (4-Oxo-chromeno[2,3-d]pyrimidin-2(5)-yl)phosphonates

Novel diethyl (4-oxo-3,4-dihydro-2H-chromeno[2,3-d]pyrimidin-2-yl)phosphonate as two enantiomers and diethyl (4-oxo-1,5-dihydro-4H-chromeno[2,3-d]pyrimidin-5-yl) phosphonate were obtained in easy procedure via reaction of 2-imino-2H-chromene-3-carboxamide, dimethylformamide dimethyl-acetal, and diethyl phosphite in a simple one pot. Possible reaction mechanisms were proposed. The structures of the obtained products were confirmed by elemental analyses and spectral tools.