Abstract
A tumor is most dangerous disease of medical science which is a mass or lumps of tissue that's formed by an accumulation of abnormal cells. A famous fractional tumor-immune model is interpreting the dynamics of tumor and effector cells. In this work, we provide a comparative and chaotic study of tumor and effector cells through fractional tumor-immune dynamical model. A new arbitrary operator based on the Mittag-Leffler law is assumed for this study. Again, we examine the interactions among distinct tumor cell inhabitants and immune structure through a model of real world problem of medical science. We First investigate the dynamical effect of the activation of the effector immune and tumor cells by using Adams-Bashforth-Moulton and Toufik-Atangana methods. Furthermore, this paper analyses the existence and uniqueness of given tumor-immune model of arbitrary order. Further, we have examined the dynamical behaviors of the fractional tumor-immunne model and obtained results are compared with exiting results by other methods. Numerical simulations are executed by Adams-Bashforth-Moulton and Toufik-Atangana methods using popular Atangana-Baleanu fractional derivative. Our obtained results will be useful for biologists to the treatment of cancer disease.
| Original language | English |
|---|---|
| Article number | 110321 |
| Journal | Chaos, Solitons and Fractals |
| Volume | 141 |
| DOIs | |
| State | Published - Dec 2020 |
| Externally published | Yes |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- AB derivative
- Adams-Bashforth-Moulton method
- Existence and uniqueness results
- Fractional tumor-immune model
- Toufik-Atangana method
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